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recombinant mouse rae1 fc chimeric protein  (R&D Systems)


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    R&D Systems recombinant mouse rae1 fc chimeric protein
    (A) Diagram showing construction of treatment (mNKG2D-2C11) and control (TZ47-2C11) bsTCEs. (B-D) MC38 (1x106) cells were injected s.c. into WT B6 mice. Treatment was initiated when tumors reached approximately 40mm2. (B) Mice received a total of four 10μg i.v injections of bsTCE every other day. (Left) Health scoring was blinded and evaluated 3h and 24h after each treatment. (Right) Weight, normalized to day 0, at the indicated time points. Data pooled from 7 experiments (n=30) (C) Mice received a total of four i.v. injections of either 2, 5 or 10μg bsTCE every other day. Health scoring was blinded and evaluated every hour for the first 8h and then 24h after each treatment. Data pooled from 2 experiments (n=8). (D) Tumor or non-tumor bearing WT B6 mice received a total of four 10μg i.v injections of bsTCE every other day. Health scoring was blinded and evaluated 3h and 24h after each treatment. Data are pooled from two experiment (n=8). (E) Representative images of <t>Rae1</t> positive staining in the liver of B6 mice or contiguous tissue sections blocked with <t>recombinant</t> Rae1. Slides counterstained with methylene blue. Health scores in B and D are shown +/− SD, weight and C are shown +/− SEM. Statistical significance determined by repeated measures two-way ANOVA with Bonferroni’s multiple comparisons test (B, C) or with Tukey multiple comparisons test (D). * p<0.05, *** p<0.001, NS = not statistically significant.
    Recombinant Mouse Rae1 Fc Chimeric Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/recombinant mouse rae1 fc chimeric protein/product/R&D Systems
    Average 90 stars, based on 7 article reviews
    recombinant mouse rae1 fc chimeric protein - by Bioz Stars, 2026-03
    90/100 stars

    Images

    1) Product Images from "Toxicity induced by a bispecific T cell redirecting protein is mediated by both T cells and myeloid cells in immunocompetent mice 2 "

    Article Title: Toxicity induced by a bispecific T cell redirecting protein is mediated by both T cells and myeloid cells in immunocompetent mice 2

    Journal: Journal of immunology (Baltimore, Md. : 1950)

    doi: 10.4049/jimmunol.1901401

    (A) Diagram showing construction of treatment (mNKG2D-2C11) and control (TZ47-2C11) bsTCEs. (B-D) MC38 (1x106) cells were injected s.c. into WT B6 mice. Treatment was initiated when tumors reached approximately 40mm2. (B) Mice received a total of four 10μg i.v injections of bsTCE every other day. (Left) Health scoring was blinded and evaluated 3h and 24h after each treatment. (Right) Weight, normalized to day 0, at the indicated time points. Data pooled from 7 experiments (n=30) (C) Mice received a total of four i.v. injections of either 2, 5 or 10μg bsTCE every other day. Health scoring was blinded and evaluated every hour for the first 8h and then 24h after each treatment. Data pooled from 2 experiments (n=8). (D) Tumor or non-tumor bearing WT B6 mice received a total of four 10μg i.v injections of bsTCE every other day. Health scoring was blinded and evaluated 3h and 24h after each treatment. Data are pooled from two experiment (n=8). (E) Representative images of Rae1 positive staining in the liver of B6 mice or contiguous tissue sections blocked with recombinant Rae1. Slides counterstained with methylene blue. Health scores in B and D are shown +/− SD, weight and C are shown +/− SEM. Statistical significance determined by repeated measures two-way ANOVA with Bonferroni’s multiple comparisons test (B, C) or with Tukey multiple comparisons test (D). * p<0.05, *** p<0.001, NS = not statistically significant.
    Figure Legend Snippet: (A) Diagram showing construction of treatment (mNKG2D-2C11) and control (TZ47-2C11) bsTCEs. (B-D) MC38 (1x106) cells were injected s.c. into WT B6 mice. Treatment was initiated when tumors reached approximately 40mm2. (B) Mice received a total of four 10μg i.v injections of bsTCE every other day. (Left) Health scoring was blinded and evaluated 3h and 24h after each treatment. (Right) Weight, normalized to day 0, at the indicated time points. Data pooled from 7 experiments (n=30) (C) Mice received a total of four i.v. injections of either 2, 5 or 10μg bsTCE every other day. Health scoring was blinded and evaluated every hour for the first 8h and then 24h after each treatment. Data pooled from 2 experiments (n=8). (D) Tumor or non-tumor bearing WT B6 mice received a total of four 10μg i.v injections of bsTCE every other day. Health scoring was blinded and evaluated 3h and 24h after each treatment. Data are pooled from two experiment (n=8). (E) Representative images of Rae1 positive staining in the liver of B6 mice or contiguous tissue sections blocked with recombinant Rae1. Slides counterstained with methylene blue. Health scores in B and D are shown +/− SD, weight and C are shown +/− SEM. Statistical significance determined by repeated measures two-way ANOVA with Bonferroni’s multiple comparisons test (B, C) or with Tukey multiple comparisons test (D). * p<0.05, *** p<0.001, NS = not statistically significant.

    Techniques Used: Injection, Staining, Recombinant



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    recombinant mouse rae1 fc chimeric protein  (R&D Systems)
    90
    R&D Systems recombinant mouse rae1 fc chimeric protein
    (A) Diagram showing construction of treatment (mNKG2D-2C11) and control (TZ47-2C11) bsTCEs. (B-D) MC38 (1x106) cells were injected s.c. into WT B6 mice. Treatment was initiated when tumors reached approximately 40mm2. (B) Mice received a total of four 10μg i.v injections of bsTCE every other day. (Left) Health scoring was blinded and evaluated 3h and 24h after each treatment. (Right) Weight, normalized to day 0, at the indicated time points. Data pooled from 7 experiments (n=30) (C) Mice received a total of four i.v. injections of either 2, 5 or 10μg bsTCE every other day. Health scoring was blinded and evaluated every hour for the first 8h and then 24h after each treatment. Data pooled from 2 experiments (n=8). (D) Tumor or non-tumor bearing WT B6 mice received a total of four 10μg i.v injections of bsTCE every other day. Health scoring was blinded and evaluated 3h and 24h after each treatment. Data are pooled from two experiment (n=8). (E) Representative images of <t>Rae1</t> positive staining in the liver of B6 mice or contiguous tissue sections blocked with <t>recombinant</t> Rae1. Slides counterstained with methylene blue. Health scores in B and D are shown +/− SD, weight and C are shown +/− SEM. Statistical significance determined by repeated measures two-way ANOVA with Bonferroni’s multiple comparisons test (B, C) or with Tukey multiple comparisons test (D). * p<0.05, *** p<0.001, NS = not statistically significant.
    Recombinant Mouse Rae1 Fc Chimeric Protein, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/recombinant mouse rae1 fc chimeric protein/product/R&D Systems
    Average 90 stars, based on 1 article reviews
    recombinant mouse rae1 fc chimeric protein - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    (A) Diagram showing construction of treatment (mNKG2D-2C11) and control (TZ47-2C11) bsTCEs. (B-D) MC38 (1x106) cells were injected s.c. into WT B6 mice. Treatment was initiated when tumors reached approximately 40mm2. (B) Mice received a total of four 10μg i.v injections of bsTCE every other day. (Left) Health scoring was blinded and evaluated 3h and 24h after each treatment. (Right) Weight, normalized to day 0, at the indicated time points. Data pooled from 7 experiments (n=30) (C) Mice received a total of four i.v. injections of either 2, 5 or 10μg bsTCE every other day. Health scoring was blinded and evaluated every hour for the first 8h and then 24h after each treatment. Data pooled from 2 experiments (n=8). (D) Tumor or non-tumor bearing WT B6 mice received a total of four 10μg i.v injections of bsTCE every other day. Health scoring was blinded and evaluated 3h and 24h after each treatment. Data are pooled from two experiment (n=8). (E) Representative images of Rae1 positive staining in the liver of B6 mice or contiguous tissue sections blocked with recombinant Rae1. Slides counterstained with methylene blue. Health scores in B and D are shown +/− SD, weight and C are shown +/− SEM. Statistical significance determined by repeated measures two-way ANOVA with Bonferroni’s multiple comparisons test (B, C) or with Tukey multiple comparisons test (D). * p<0.05, *** p<0.001, NS = not statistically significant.

    Journal: Journal of immunology (Baltimore, Md. : 1950)

    Article Title: Toxicity induced by a bispecific T cell redirecting protein is mediated by both T cells and myeloid cells in immunocompetent mice 2

    doi: 10.4049/jimmunol.1901401

    Figure Lengend Snippet: (A) Diagram showing construction of treatment (mNKG2D-2C11) and control (TZ47-2C11) bsTCEs. (B-D) MC38 (1x106) cells were injected s.c. into WT B6 mice. Treatment was initiated when tumors reached approximately 40mm2. (B) Mice received a total of four 10μg i.v injections of bsTCE every other day. (Left) Health scoring was blinded and evaluated 3h and 24h after each treatment. (Right) Weight, normalized to day 0, at the indicated time points. Data pooled from 7 experiments (n=30) (C) Mice received a total of four i.v. injections of either 2, 5 or 10μg bsTCE every other day. Health scoring was blinded and evaluated every hour for the first 8h and then 24h after each treatment. Data pooled from 2 experiments (n=8). (D) Tumor or non-tumor bearing WT B6 mice received a total of four 10μg i.v injections of bsTCE every other day. Health scoring was blinded and evaluated 3h and 24h after each treatment. Data are pooled from two experiment (n=8). (E) Representative images of Rae1 positive staining in the liver of B6 mice or contiguous tissue sections blocked with recombinant Rae1. Slides counterstained with methylene blue. Health scores in B and D are shown +/− SD, weight and C are shown +/− SEM. Statistical significance determined by repeated measures two-way ANOVA with Bonferroni’s multiple comparisons test (B, C) or with Tukey multiple comparisons test (D). * p<0.05, *** p<0.001, NS = not statistically significant.

    Article Snippet: Contiguous sections from each sample were incubated with primary antibodies pre-incubated for 4 hours with recombinant mouse Rae1 Fc chimeric protein (R&D Systems, 1998-RA) at a 1:10 molar ratio as specificity controls.

    Techniques: Injection, Staining, Recombinant